Antithrombogenicity of immobilized Urokinase
نویسندگان
چکیده
منابع مشابه
TREATMENT OF SPONTANEOUS INTRACRANIAL HEMORRHAGE USING UROKINASE
Twenty patients with intracranial hematoma (ICH or IVH) were treated with direct infusion of urokinase through a catheter. Reduction of hematoma volume was observed within a few days. Twelve patients showed good or excellent outcome. No infection or rebleeding was observed.
متن کاملComplexes Lysis of Plasma Clots by Urokinase - Soluble Urokinase Receptor
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متن کاملLysis of plasma clots by urokinase-soluble urokinase receptor complexes.
Single-chain urokinase plasminogen activator (scuPA), the unique form secreted by cells, expresses little intrinsic plasminogen activator activity. scuPA can be activated by proteolytic cleavage to form a two-chain enzyme (tcuPA), which is susceptible to inhibition by plasminogen activator inhibitor type I (PAI-1). scuPA is also activated when it binds to its cellular receptor (uPAR), in which ...
متن کاملtreatment of spontaneous intracranial hemorrhage using urokinase
twenty patients with intracranial hematoma (ich or ivh) were treated with direct infusion of urokinase through a catheter. reduction of hematoma volume was observed within a few days. twelve patients showed good or excellent outcome. no infection or rebleeding was observed.
متن کاملPharmacology of thrombolysis: urokinase.
and animal plasminogen into plasmin (Fig. 1) as well as the hydrolysis of lysine and arginine esters; the esterolytic activity of the activator, in contrast to plasmin, is not inhibited by soybean trypsininhibitor. Its active site is not accessible to bigger molecules, as evidenced-by a strong reduction of its proteolytic activity compared with plasmin. Fibrin, for example, is cleaved not at al...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1978
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.9.504